I am a postdoctoral researcher working with Cole Trapnell and Jay Shendure at University of Washington. Before that I received my Ph.D. from Stanford University, where I studied complex traits in the lab of Jonathan Pritchard. With my free time I like to dabble with watercolor painting and go hiking.
I enjoy thinking about how DNA is translated into life. Specifically, I am interested in understanding gene regulation and the development of complex traits.
TransMPRA: A framework for assaying the role of many trans-acting factors at many enhancers. Calderon, Diego, Andria Ellis, Riza M. Daza, Beth Martin, Jacob M. Tome, Wei Chen, Florence M. Chardon, Anh Leith, Choli Lee, Beth Martin, Cole Trapnell, Jay Shendure. BioRxiv. [bioRxiv][pdf]
Systematic reconstruction of the cellular trajectories of mammalian embryogenesis. Qiu, Chengxiang, Junyue Cao, Tony Li, Sanjay Srivatsan, Xingfan Huang, Diego Calderon, William Stafford Noble, Christine M. Disteche, Malte Spielmann, Cecilia B. Moens, Cole Trapnell, Jay Shendure. BioRxiv. [bioRxiv][pdf]
Ancient Rome: A genetic crossroads of Europe and the Mediterranean. Antonio ML, Gao Z, Moots HM, Lucci M, Candilio F, Sawyer S, Oberreiter V, Calderon D, Devitofranceschi K, Aikens RC, Aneli S, et al. Published in Science. [NCBI][Journal site]
Landscape of stimulation-responsive chromatin across diverse human immune cells. Calderon, Diego*, Michelle L.T. Nguyen*, Anja Mezger*, Arwa Kathiria, Fabian Müller, Vinh Nguyen, Ninnia Lescano, Beijing Wu, John Trombetta, Jessica V. Ribado, David A. Knowles, Ziyue Gao, Franziska Blaeschke, Audrey V. Parent, Trevor D. Burt, Mark S. Anderson, Lindsey A. Criswell, William J. Greenleaf, Alexander Marson, Jonathan K. Pritchard. Published in Nature Genetics. [NCBI][Journal site][pdf]
Impact of regulatory variation across human iPSCs and differentiated cells. Banovich, Nicholas E., Yang I. Li, Anil Raj, Michelle C. Ward, Peyton Greenside, Diego Calderon, Po Yuan Tung et al. Published in Genome Research. [NCBI][Journal site]
Inferring Relevant Cell Types for Complex Traits by Using Single-Cell Gene Expression. Calderon, Diego, Anand Bhaskar, David A. Knowles, David Golan, Towfique Raj, Audrey Q. Fu, and Jonathan K. Pritchard. Published in American Journal of Human Genetics. [NCBI][Journal site][pdf][software: CRAN][software: github repository]
The king cobra genome reveals dynamic gene evolution and adaptation in the snake venom system. Vonk, Freek J., Nicholas R. Casewell, Christiaan V. Henkel, Alysha M. Heimberg, Hans J. Jansen, Ryan JR McCleary, Harald ME Kerkkamp, et al. Published in Proceedings of the National Academy of Sciences. [NCBI][Journal site]
* Indicates co-authorship.