I am a postdoctoral researcher working with Cole Trapnell and Jay Shendure at University of Washington. Before that I received my Ph.D. from Stanford University where I studied complex traits in the lab of Jonathan Pritchard. With my free time I like to dabble in watercolors and go hiking.
I enjoy thinking about how DNA is translated into life. Specifically, I am interested in understanding gene regulation and the development of complex traits.
Landscape of stimulation-responsive chromatin across diverse human immune cells. Calderon, Diego, Michelle L.T. Nguyen, Anja Mezger, Arwa Kathiria, Vinh Nguyen, Ninnia Lescano, Beijing Wu, John Trombetta, Jessica V. Ribado, David A. Knowles, Ziyue Gao, Audrey V. Parent, Trevor D. Burt, Mark S. Anderson, Lindsey A. Criswell, William J. Greenleaf, Alexander Marson, Jonathan K. Pritchard. Available on bioRxiv. [bioRxiv]
Impact of regulatory variation across human iPSCs and differentiated cells. Banovich, Nicholas E., Yang I. Li, Anil Raj, Michelle C. Ward, Peyton Greenside, Diego Calderon, Po Yuan Tung et al. Published in Genome Research. [NCBI]
Inferring Relevant Cell Types for Complex Traits by Using Single-Cell Gene Expression. Calderon, Diego, Anand Bhaskar, David A. Knowles, David Golan, Towfique Raj, Audrey Q. Fu, and Jonathan K. Pritchard. Published in American Journal of Human Genetics. [NCBI][pdf][software: CRAN][software: github repository]
The king cobra genome reveals dynamic gene evolution and adaptation in the snake venom system. Vonk, Freek J., Nicholas R. Casewell, Christiaan V. Henkel, Alysha M. Heimberg, Hans J. Jansen, Ryan JR McCleary, Harald ME Kerkkamp, et al. Published in Proceedings of the National Academy of Sciences. [NCBI]